Chemogenesis of an antiangiogenic glycosaminoglycan.
ACS Med Chem Lett
; 5(6): 644-6, 2014 Jun 12.
Article
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| MEDLINE
| ID: mdl-24944736
ABSTRACT
In this letter we report a facile chemical conversion of heparin, a potent anticoagulant with minimal antiangiogenic activity, into an effective antiangiogenic glycosaminoglycan through optimized chemical approaches. This work highlights the potential for industrial scale production of a therapeutic anticancer glycosaminoglycan.
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MEDLINE
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En
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2014
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Article