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Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria.
Zhang, Qingfeng; Siegel, T Nicolai; Martins, Rafael M; Wang, Fei; Cao, Jun; Gao, Qi; Cheng, Xiu; Jiang, Lubin; Hon, Chung-Chau; Scheidig-Benatar, Christine; Sakamoto, Hiroshi; Turner, Louise; Jensen, Anja T R; Claes, Aurelie; Guizetti, Julien; Malmquist, Nicholas A; Scherf, Artur.
  • Zhang Q; 1] Research Center for Translational Medicine, Shanghai East Hospital and Institute of Infectious Diseases and Vaccine Development, Tongji University School of Medicine, Shanghai 200120, China [2] Unité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, F-75724 Paris, France [3] CNRS, URA
  • Siegel TN; 1] Unité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, F-75724 Paris, France [2] CNRS, URA 2581, F-75724 Paris, France [3] Research Center for Infectious Diseases, University of Würzburg, 97080 Würzburg, Germany.
  • Martins RM; 1] Unité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, F-75724 Paris, France [2] CNRS, URA 2581, F-75724 Paris, France.
  • Wang F; Research Center for Translational Medicine, Shanghai East Hospital and Institute of Infectious Diseases and Vaccine Development, Tongji University School of Medicine, Shanghai 200120, China.
  • Cao J; Jiangsu Institute of Parasitic Diseases, Key Laboratory of Parasitic Disease Control and Prevention (Ministry of Health), and Jiangsu Provincial Key Laboratory of Parasite Molecular Biology, Wuxi 214064, China.
  • Gao Q; Jiangsu Institute of Parasitic Diseases, Key Laboratory of Parasitic Disease Control and Prevention (Ministry of Health), and Jiangsu Provincial Key Laboratory of Parasite Molecular Biology, Wuxi 214064, China.
  • Cheng X; Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China.
  • Jiang L; Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China.
  • Hon CC; Cell Biology of Parasitism Unit, Institut Pasteur, and INSERM U786, F-75724 Paris, France.
  • Scheidig-Benatar C; 1] Unité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, F-75724 Paris, France [2] CNRS, URA 2581, F-75724 Paris, France.
  • Sakamoto H; 1] Unité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, F-75724 Paris, France [2] CNRS, URA 2581, F-75724 Paris, France.
  • Turner L; Centre for Medical Parasitology, Department of International Health, Immunology &Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
  • Jensen AT; Centre for Medical Parasitology, Department of International Health, Immunology &Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
  • Claes A; 1] Unité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, F-75724 Paris, France [2] CNRS, URA 2581, F-75724 Paris, France.
  • Guizetti J; 1] Unité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, F-75724 Paris, France [2] CNRS, URA 2581, F-75724 Paris, France.
  • Malmquist NA; 1] Unité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, F-75724 Paris, France [2] CNRS, URA 2581, F-75724 Paris, France.
  • Scherf A; 1] Unité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, F-75724 Paris, France [2] CNRS, URA 2581, F-75724 Paris, France.
Nature ; 513(7518): 431-5, 2014 Sep 18.
Article en En | MEDLINE | ID: mdl-25043062
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / ARN Protozoario / Malaria Cerebral / Genes Protozoarios / Silenciador del Gen / Exorribonucleasas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2014 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / ARN Protozoario / Malaria Cerebral / Genes Protozoarios / Silenciador del Gen / Exorribonucleasas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2014 Tipo del documento: Article