Portable lactate analyzer for measuring lactate in cerebrospinal fluid (CSF) and plasma - method-comparison evaluations.
Arq Neuropsiquiatr
; 72(7): 500-5, 2014 Jul.
Article
en En
| MEDLINE
| ID: mdl-25054981
ABSTRACT
UNLABELLED Increased plasma lactate levels can indicate the presence of metabolic disorders in HIV infected individuals. OBJECTIVE:
To determine whether a portable analyzer is valid for measuring cerebrospinal fluid (CSF) and plasma lactate levels in HIV infected individuals.METHOD:
CSF and plasma were collected from 178 subjects. Samples tested by the Accutrend portable analyzer were compared to those tested by a reference device (SYNCHRON LX 20).RESULTS:
The portable analyzer had in plasma sensitivity of 0.95 and specificity 0.87. For CSF the specificity was 0.95; the sensitivity 0.33; the negative predictive value was 95% and the positive predictive value 33%.CONCLUSIONS:
These findings support the validity of the portable analyzer in measuring lactate concentrations in CSF that fall within the normal range. The relatively poor positive predictive value indicates that a result above the reference range may represent a "false positive test", and should be confirmed by the reference device before concluding abnormality.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Infecciones por VIH
/
Sistemas de Atención de Punto
/
Ácido Láctico
Tipo de estudio:
Prognostic_studies
Límite:
Adult
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Año:
2014
Tipo del documento:
Article