C-terminal agrin fragment is inversely related to neuromuscular fatigue in older men.
Muscle Nerve
; 51(1): 132-3, 2015 Jan.
Article
en En
| MEDLINE
| ID: mdl-25186664
ABSTRACT
INTRODUCTION:
The aim of this study was to examine the relationship between serum C-terminal agrin fragment (CAF) concentrations and neuromuscular fatigue in older adults.METHODS:
Twenty-two healthy older men and women volunteered for this study. Resting fasted blood samples were collected and prepared for measurement of serum CAF concentration by a commercially available ELISA kit. The onset of neuromuscular fatigue was measured by monitoring electromyographic fatigue curves from the vastus lateralis muscle using the physical working capacity at fatigue threshold (PWCFT ) test.RESULTS:
A significant inverse correlation for men was observed between CAF and PWCFT (r = -0.602; P = 0.05), but not for women (r = 0.208; P = 0.54). After controlling for age and body mass index, significant correlations (r = -0.69; P = 0.042) remained for men, but not for women (r = 0.12; P = 0.76).CONCLUSIONS:
These data suggest that serum CAF concentrations were significantly related to the onset of neuromuscular fatigue independent of age and BMI in men only.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Agrina
/
Fatiga Muscular
/
Fatiga
Límite:
Aged
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Aged80
/
Female
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Humans
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Male
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Middle aged
Idioma:
En
Año:
2015
Tipo del documento:
Article