Recurrent life-threatening reactions to platelet transfusion in an aplastic anaemia patient with a paroxysmal nocturnal haemoglobinuria clone.
Intern Med J
; 44(9): 925-7, 2014 Sep.
Article
en En
| MEDLINE
| ID: mdl-25201425
ABSTRACT
A 60-year-old woman was diagnosed with non-severe aplastic anaemia when she presented with anaemia and thrombocytopenia. She developed recurrent life-threatening hypotensive reactions during transfusion of leukodepleted platelet concentrates, and washed platelet concentrates prevented the development of such reactions subsequently. A paroxysmal nocturnal haemoglobinuria clone was detected on investigating for aplastic anaemia, which has been speculated to play a role in the recurrent hypotensive reactions.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Proteínas del Sistema Complemento
/
Células Clonales
/
Transfusión de Plaquetas
/
Hemoglobinuria Paroxística
/
Anemia Aplásica
Tipo de estudio:
Etiology_studies
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Año:
2014
Tipo del documento:
Article