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Energetic dissection of Gleevec's selectivity toward human tyrosine kinases.
Agafonov, Roman V; Wilson, Christopher; Otten, Renee; Buosi, Vanessa; Kern, Dorothee.
  • Agafonov RV; 1] Howard Hughes Medical Institute, Department of Biochemistry, Brandeis University, Waltham, Massachusetts, USA. [2].
  • Wilson C; 1] Howard Hughes Medical Institute, Department of Biochemistry, Brandeis University, Waltham, Massachusetts, USA. [2].
  • Otten R; Howard Hughes Medical Institute, Department of Biochemistry, Brandeis University, Waltham, Massachusetts, USA.
  • Buosi V; Howard Hughes Medical Institute, Department of Biochemistry, Brandeis University, Waltham, Massachusetts, USA.
  • Kern D; Howard Hughes Medical Institute, Department of Biochemistry, Brandeis University, Waltham, Massachusetts, USA.
Nat Struct Mol Biol ; 21(10): 848-53, 2014 Oct.
Article en En | MEDLINE | ID: mdl-25218445
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperazinas / Pirimidinas / Termodinámica / Benzamidas / Proteínas Proto-Oncogénicas c-abl / Inhibidores de Proteínas Quinasas / Neoplasias / Antineoplásicos Límite: Humans Idioma: En Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperazinas / Pirimidinas / Termodinámica / Benzamidas / Proteínas Proto-Oncogénicas c-abl / Inhibidores de Proteínas Quinasas / Neoplasias / Antineoplásicos Límite: Humans Idioma: En Año: 2014 Tipo del documento: Article