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SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age.
Van Meter, Michael; Kashyap, Mehr; Rezazadeh, Sarallah; Geneva, Anthony J; Morello, Timothy D; Seluanov, Andrei; Gorbunova, Vera.
  • Van Meter M; Department of Biology, University of Rochester, Rochester, New York 14627, USA.
  • Kashyap M; Department of Biology, University of Rochester, Rochester, New York 14627, USA.
  • Rezazadeh S; Department of Biology, University of Rochester, Rochester, New York 14627, USA.
  • Geneva AJ; Department of Biology, University of Rochester, Rochester, New York 14627, USA.
  • Morello TD; Department of Biology, University of Rochester, Rochester, New York 14627, USA.
  • Seluanov A; Department of Biology, University of Rochester, Rochester, New York 14627, USA.
  • Gorbunova V; Department of Biology, University of Rochester, Rochester, New York 14627, USA.
Nat Commun ; 5: 5011, 2014 Sep 23.
Article en En | MEDLINE | ID: mdl-25247314

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / Estrés Fisiológico / Envejecimiento / Proteínas Nucleares / Elementos de Nucleótido Esparcido Largo / Sirtuinas Límite: Animals Idioma: En Año: 2014 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / Estrés Fisiológico / Envejecimiento / Proteínas Nucleares / Elementos de Nucleótido Esparcido Largo / Sirtuinas Límite: Animals Idioma: En Año: 2014 Tipo del documento: Article