[Research of bimingan granule on dendritic cell in allergic rhinitis mice].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
; 28(13): 983-5, 2014 Jul.
Article
en Zh
| MEDLINE
| ID: mdl-25248267
ABSTRACT
OBJECTIVE:
To investigate the mechanism.METHOD:
We isolate the mouse bone marrow cells and cultured with rGM-CSF and rIL-4 to stimulate bone marrow cells to transfer to immature dendritic cells. And then the immature dendritic cells were costimulated with ILPS and different concentrations of Bimingan Granule.RESULT:
MHC II, CD80, CD86 were detected by flow cytometer and TNF-alpha, IL-1beta, IL-6 and IL-10 were quantified by ELISA.CONCLUSION:
Our results showed that Bimingan Granule may significantly inhibit the differentiation of immature dendritic cells to mature dendritic cells.
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Banco de datos:
MEDLINE
Asunto principal:
Células Dendríticas
/
Medicamentos Herbarios Chinos
/
Rinitis Alérgica
Límite:
Animals
Idioma:
Zh
Año:
2014
Tipo del documento:
Article