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A lysosome-targeted fluorescent chemodosimeter for monitoring endogenous and exogenous hydrogen sulfide by in vivo imaging.
Zou, Xiao Ju; Ma, Yi Cheng; Guo, Lin E; Liu, Wen Xiang; Liu, Mei Juan; Zou, Cheng Gang; Zhou, Ying; Zhang, Jun Feng.
  • Zou XJ; College of Chemical Science and Technology, Yunnan University, Kunming 650091, PR China. yingzhou@ynu.edu.cn.
Chem Commun (Camb) ; 50(89): 13833-6, 2014 Nov 18.
Article en En | MEDLINE | ID: mdl-25255077
ABSTRACT
A lysosome-targeted fluorescent chemodosimeter, 1, was developed for monitoring endogenous and exogenous H2S by in vivo imaging of HeLa cells, D. melanogaster and C. elegans. In the tests of mutated C. elegans (SRP-6 nulls), chemodosimeter 1 could trace the accumulation of lysosome and lysosomal injury with a high resolution.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Caenorhabditis elegans / Cumarinas / Drosophila melanogaster / Colorantes Fluorescentes / Sulfuro de Hidrógeno / Lisosomas Límite: Animals / Humans Idioma: En Año: 2014 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Caenorhabditis elegans / Cumarinas / Drosophila melanogaster / Colorantes Fluorescentes / Sulfuro de Hidrógeno / Lisosomas Límite: Animals / Humans Idioma: En Año: 2014 Tipo del documento: Article