A lysosome-targeted fluorescent chemodosimeter for monitoring endogenous and exogenous hydrogen sulfide by in vivo imaging.
Chem Commun (Camb)
; 50(89): 13833-6, 2014 Nov 18.
Article
en En
| MEDLINE
| ID: mdl-25255077
ABSTRACT
A lysosome-targeted fluorescent chemodosimeter, 1, was developed for monitoring endogenous and exogenous H2S by in vivo imaging of HeLa cells, D. melanogaster and C. elegans. In the tests of mutated C. elegans (SRP-6 nulls), chemodosimeter 1 could trace the accumulation of lysosome and lysosomal injury with a high resolution.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Caenorhabditis elegans
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Cumarinas
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Drosophila melanogaster
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Colorantes Fluorescentes
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Sulfuro de Hidrógeno
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Lisosomas
Límite:
Animals
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Humans
Idioma:
En
Año:
2014
Tipo del documento:
Article