Trienamines derived from 5-substituted furfurals: remote ε-functionalization of 2,4-dienals.
Org Biomol Chem
; 12(46): 9324-8, 2014 Dec 14.
Article
en En
| MEDLINE
| ID: mdl-25322451
ABSTRACT
The selective ε-functionalization of 5-substituted furfurals via trienamine intermediates is reported herein. This methodology was successfully applied to several 5-substituted furfurals with different amines via formation of a trienamine through the furan ring. The rationalized reaction mechanism involves the addition of the trienamine intermediate to its corresponding iminium-ion producing new furan-containing scaffolds.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Furaldehído
/
Furanos
/
Aminas
/
Iminas
Idioma:
En
Año:
2014
Tipo del documento:
Article