Template-directed oligomerization catalyzed by a polynucleotide analog.
Science
; 244(4902): 329-31, 1989 Apr 21.
Article
en En
| MEDLINE
| ID: mdl-2540527
ABSTRACT
A pyrophosphate-linked analog of polycytidylic acid has been synthesized and shown to catalyze the oligomerization of the complementary monomer 2'-deoxyguanosine 3',5'-bisphosphoimidazolide. Analogs of polynucleotides are of interest in studies of the origins of life as possible precursors of the first RNA molecules. These results demonstrate that such molecules are capable of serving as templates for further synthesis.
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Banco de datos:
MEDLINE
Asunto principal:
Poli C
/
Polirribonucleótidos
Idioma:
En
Año:
1989
Tipo del documento:
Article