Autofagia; Interleucina-1beta/metabolismo; Ubiquitina-Proteína Ligasas/metabolismo; Adenosina Trifosfatasas/metabolismo; Animales; Línea Celular; Citocinas/metabolismo; Inmunidad Innata; Inflamación; Lipopolisacáridos/metabolismo; Macrófagos/metabolismo; Ratones; Naftiridinas/metabolismo; Mutación Puntual; ARN Mensajero/metabolismo; ARN Interferente Pequeño/metabolismo; Sepsis/metabolismo; Transducción de Señal; Receptor Toll-Like 4/metabolismo; Ubiquitina/metabolismo

ACTB, actin, beta; ATG7, autophagy-related 7; BECN1, Beclin 1, autophagy related; Baf A1, bafilomycin A1; CHX, cycloheximide; Epoxo, epoxomycin; HBSS, Hank's balanced salt solution; IL1B, interleukin 1, beta; IRAKs, interleukin-1 receptor-associated kinases; LAMP2, lysosomal-associated membrane protein 2; LPS; LPS, lipopolysaccharide; MAP1LC3B, microtubule-associated protein 1 light chain 3 beta; MAP3K14, mitogen-activated protein kinase kinase kinase 14; MAP3K7, mitogen-activated protein kinase kinase kinase 7; MAPK1/3, mitogen-activated protein kinase 1/3; MAPK14, mitogen-activated protein kinase 14; MAPK8/9, mitogen-activated protein kinase 8/9; MTOR, mechanistic target of rapamycin (serine/threonine kinase); MYD88, myeloid differentiation primary response 88; MΦ, macrophages; NFE2L2, nuclear factor, erythroid 2-like 2; NFKB, nuclear factor of kappa light polypeptide gene enhancer in B-cells; NLRP3, NLR family, pyrin domain containing 3; PELI3; PELI3, pellino E3 ubiquitin protein ligase family member 3; PRRs, pattern recognition receptors; RIPK1, receptor (TNFRSF)-interacting serine-threonine kinase 1; Rapa, rapamycin; SQSTM1; SQSTM1, sequestosome 1; TABs, TGF-beta activated kinase 1/MAP3K7 binding protein 1/2/3; TBK1, TANK-binding kinase 1; TICAM1, toll-like receptor adaptor molecule 1; TLRs, toll-like receptors; TNF, tumor necrosis factor; TRAF6, TNF receptor-associated factor 6, E3 ubiquitin protein ligase; TUBB, tubulin, beta class I; Torin2; UBB, ubiquitin B; WT, wildtype; Wortm, wortmannin; autophagy