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Synthesis and evaluation of NS5A inhibitors containing diverse heteroaromatic cores.
Henderson, James A; Bilimoria, Darius; Bubenik, Monica; Cadilhac, Caroline; Cottrell, Kevin M; Denis, Francois; Dietrich, Evelyne; Ewing, Nigel; Falardeau, Guy; Giroux, Simon; L'Heureux, Lucille; Liu, Bingcan; Mani, Nagraj; Morris, Mark; Nicolas, Olivier; Pereira, Oswy Z; Poisson, Carl; Reddy, T Jagadeeswar; Selliah, Subajini; Shawgo, Rebecca S; Vaillancourt, Louis; Wang, Jian; Xu, Jinwang; Chauret, Nathalie; Berlioz-Seux, Francoise; Chan, Laval C; Das, Sanjoy K; Grillot, Anne-Laure; Bennani, Youssef L; Maxwell, John P.
  • Henderson JA; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA. Electronic address: james_henderson@vrtx.com.
  • Bilimoria D; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Bubenik M; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Cadilhac C; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Cottrell KM; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA.
  • Denis F; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Dietrich E; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Ewing N; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA.
  • Falardeau G; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Giroux S; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA.
  • L'Heureux L; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Liu B; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Mani N; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA.
  • Morris M; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA.
  • Nicolas O; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Pereira OZ; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Poisson C; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Reddy TJ; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Selliah S; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Shawgo RS; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA.
  • Vaillancourt L; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Wang J; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA.
  • Xu J; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA.
  • Chauret N; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Berlioz-Seux F; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA.
  • Chan LC; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Das SK; Vertex Pharmaceuticals Canada Incorporated, 275 Boul. Armand-Frappier, Laval, QC H7V 4A7, Canada.
  • Grillot AL; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA.
  • Bennani YL; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA.
  • Maxwell JP; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA.
Bioorg Med Chem Lett ; 25(4): 948-51, 2015 Feb 15.
Article en En | MEDLINE | ID: mdl-25577039
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Proteínas no Estructurales Virales / Hepacivirus Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Proteínas no Estructurales Virales / Hepacivirus Idioma: En Año: 2015 Tipo del documento: Article