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Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease.
Southwell, Amber L; Franciosi, Sonia; Villanueva, Erika B; Xie, Yuanyun; Winter, Laurie A; Veeraraghavan, Janaki; Jonason, Alan; Felczak, Boguslaw; Zhang, Weining; Kovalik, Vlad; Waltl, Sabine; Hall, George; Pouladi, Mahmoud A; Smith, Ernest S; Bowers, William J; Zauderer, Maurice; Hayden, Michael R.
  • Southwell AL; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.
  • Franciosi S; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.
  • Villanueva EB; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.
  • Xie Y; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.
  • Winter LA; Vaccinex, Inc., Rochester, NY 14620, USA.
  • Veeraraghavan J; Vaccinex, Inc., Rochester, NY 14620, USA.
  • Jonason A; Vaccinex, Inc., Rochester, NY 14620, USA.
  • Felczak B; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.
  • Zhang W; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.
  • Kovalik V; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.
  • Waltl S; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.
  • Hall G; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.
  • Pouladi MA; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, 138648, Singapore; Department of Medicine, National University of Singapore, Singapore.
  • Smith ES; Vaccinex, Inc., Rochester, NY 14620, USA.
  • Bowers WJ; Vaccinex, Inc., Rochester, NY 14620, USA.
  • Zauderer M; Vaccinex, Inc., Rochester, NY 14620, USA.
  • Hayden MR; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada. Electronic address: mrh@cmmt.ubc.ca.
Neurobiol Dis ; 76: 46-56, 2015 Apr.
Article en En | MEDLINE | ID: mdl-25662335

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antígenos CD / Enfermedad de Huntington / Semaforinas / Anticuerpos Monoclonales Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antígenos CD / Enfermedad de Huntington / Semaforinas / Anticuerpos Monoclonales Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article