Association between coeliac disease and psoriasis: Italian primary care multicentre study.
Dermatology
; 230(2): 156-60, 2015.
Article
en En
| MEDLINE
| ID: mdl-25662711
ABSTRACT
BACKGROUND:
Studies assessing the association between coeliac disease (CD) and psoriasis show conflicting results.OBJECTIVE:
To assess in the primary care setting the prevalence of CD in patients with psoriasis and the response to a gluten-free diet (GFD) in subjects with psoriasis and CD.METHODS:
We enrolled 218 patients with psoriasis and 264 controls. Coeliac screening was carried out in all subjects (Eurospital, Trieste, Italy). In subjects with a positive serology, the diagnosis of CD was confirmed histologically.RESULTS:
Nine (4.1%) psoriatic patients had positive anti-tissue transglutaminase antibodies compared to only 1 among controls (0.4%, p < 0.05; OR 2.03, 95% CI 1.42-90.11). The diagnosis of CD was confirmed histologically in all 10 subjects. At 6 months GFD was associated with a great improvement of skin lesions in 7 out of 8 patients with psoriasis.CONCLUSION:
Our multicentre primary care study showed an high prevalence of CD in psoriasis and an improvement of skin lesions in CD under GFD.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Psoriasis
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Enfermedad Celíaca
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Dieta Sin Gluten
Tipo de estudio:
Clinical_trials
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Diagnostic_studies
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Observational_studies
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Prevalence_studies
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Risk_factors_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
/
Middle aged
País como asunto:
Europa
Idioma:
En
Año:
2015
Tipo del documento:
Article