Coupling a solid phase microextraction (SPME) probe with ambient MS for rapid enrichment and detection of phosphopeptides in biological samples.
Analyst
; 140(8): 2599-602, 2015 Apr 21.
Article
en En
| MEDLINE
| ID: mdl-25692184
ABSTRACT
In this study, we developed a probe-electrospray ionization method by coupling a SPME probe modified with nanosized TiO2 directly to nanoESI-MS for the phosphoproteome analysis, which demonstrated excellent selectivity and sensitivity for enrichment of phosphopeptides in complex biological samples.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Fosfopéptidos
/
Espectrometría de Masa por Ionización de Electrospray
/
Proteómica
/
Microextracción en Fase Sólida
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Año:
2015
Tipo del documento:
Article