Nonsynonymous single nucleotide polymorphisms of NHE3 differentially decrease NHE3 transporter activity.

Zhu, Xinjun Cindy; Sarker, Rafiquel; Horton, John R; Chakraborty, Molee; Chen, Tian-E; Tse, C Ming; Cha, Boyoung; Donowitz, Mark

Zhu, Xinjun Cindy; Sarker, Rafiquel; Horton, John R; Chakraborty, Molee; Chen, Tian-E; Tse, C Ming; Cha, Boyoung; Donowitz, Mark.

Zhu XC; Department of Medicine, Division of Gastroenterology and Hepatology, Center of Cardiovascular Sciences, Albany Medical Center, Albany, New York; Departments of Physiology and Medicine, Division of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Sarker R; Departments of Physiology and Medicine, Division of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Horton JR; Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia.
Chakraborty M; Departments of Physiology and Medicine, Division of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Chen TE; Departments of Physiology and Medicine, Division of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Tse CM; Departments of Physiology and Medicine, Division of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Cha B; Departments of Physiology and Medicine, Division of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Donowitz M; Departments of Physiology and Medicine, Division of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, Maryland; and mdonowit@JHMI.edu.

Am J Physiol Cell Physiol ; 308(9): C758-66, 2015 May 01.

Article en En | MEDLINE | ID: mdl-25715704

Asunto(s)

Membrana Celular/metabolismo; Polimorfismo de Nucleótido Simple; Intercambiadores de Sodio-Hidrógeno/genética; Intercambiadores de Sodio-Hidrógeno/metabolismo; 8-Bromo Monofosfato de Adenosina Cíclica/farmacología; Animales; Transporte Biológico; Proteínas de Unión al Calcio/genética; Proteínas de Unión al Calcio/metabolismo; Línea Celular; Membrana Celular/efectos de los fármacos; Dexametasona/farmacología; Regulación hacia Abajo; Genotipo; Humanos; Mutación; Fenotipo; Unión Proteica; Transporte de Proteínas; Conejos; Intercambiador 3 de Sodio-Hidrógeno; Intercambiadores de Sodio-Hidrógeno/efectos de los fármacos; Transfección

Palabras clave

CHP; NHE3; SNP; dexamethasone

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Membrana Celular / Intercambiadores de Sodio-Hidrógeno / Polimorfismo de Nucleótido Simple Límite: Animals / Humans Idioma: En Año: 2015 Tipo del documento: Article

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