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Human monocytes undergo functional re-programming during sepsis mediated by hypoxia-inducible factor-1α.
Shalova, Irina N; Lim, Jyue Yuan; Chittezhath, Manesh; Zinkernagel, Annelies S; Beasley, Federico; Hernández-Jiménez, Enrique; Toledano, Victor; Cubillos-Zapata, Carolina; Rapisarda, Annamaria; Chen, Jinmiao; Duan, Kaibo; Yang, Henry; Poidinger, Michael; Melillo, Giovanni; Nizet, Victor; Arnalich, Francisco; López-Collazo, Eduardo; Biswas, Subhra K.
  • Shalova IN; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Biopolis, #04-06 Immunos building, 8A Biomedical Grove, Singapore 138648, Singapore.
  • Lim JY; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Biopolis, #04-06 Immunos building, 8A Biomedical Grove, Singapore 138648, Singapore.
  • Chittezhath M; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Biopolis, #04-06 Immunos building, 8A Biomedical Grove, Singapore 138648, Singapore.
  • Zinkernagel AS; Department of Pediatrics and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Beasley F; Department of Pediatrics and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Hernández-Jiménez E; Tumor Immunology Lab and Innate Immunity Group, IdiPAZ, "La Paz" Hospital, Pseo de La Castellana 261, Madrid 28046, Spain.
  • Toledano V; Tumor Immunology Lab and Innate Immunity Group, IdiPAZ, "La Paz" Hospital, Pseo de La Castellana 261, Madrid 28046, Spain.
  • Cubillos-Zapata C; Tumor Immunology Lab and Innate Immunity Group, IdiPAZ, "La Paz" Hospital, Pseo de La Castellana 261, Madrid 28046, Spain.
  • Rapisarda A; Development Therapeutic Program, Tumor Hypoxia Laboratory, Science Applications International Corporation-Frederick, Inc., National Cancer Institute, Frederick, MD 21701, USA.
  • Chen J; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Biopolis, #04-06 Immunos building, 8A Biomedical Grove, Singapore 138648, Singapore.
  • Duan K; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Biopolis, #04-06 Immunos building, 8A Biomedical Grove, Singapore 138648, Singapore.
  • Yang H; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Biopolis, #04-06 Immunos building, 8A Biomedical Grove, Singapore 138648, Singapore.
  • Poidinger M; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Biopolis, #04-06 Immunos building, 8A Biomedical Grove, Singapore 138648, Singapore.
  • Melillo G; Development Therapeutic Program, Tumor Hypoxia Laboratory, Science Applications International Corporation-Frederick, Inc., National Cancer Institute, Frederick, MD 21701, USA.
  • Nizet V; Department of Pediatrics and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Arnalich F; Department of Internal Medicine, "La Paz" Hospital, Pseo de La Castellana 261, Madrid 28046, Spain.
  • López-Collazo E; Tumor Immunology Lab and Innate Immunity Group, IdiPAZ, "La Paz" Hospital, Pseo de La Castellana 261, Madrid 28046, Spain.
  • Biswas SK; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Biopolis, #04-06 Immunos building, 8A Biomedical Grove, Singapore 138648, Singapore. Electronic address: subhra_biswas@immunol.a-star.edu.sg.
Immunity ; 42(3): 484-98, 2015 Mar 17.
Article en En | MEDLINE | ID: mdl-25746953
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Huésped Inmunocomprometido / Sepsis / Subunidad alfa del Factor 1 Inducible por Hipoxia / Quinasas Asociadas a Receptores de Interleucina-1 / Reprogramación Celular Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Huésped Inmunocomprometido / Sepsis / Subunidad alfa del Factor 1 Inducible por Hipoxia / Quinasas Asociadas a Receptores de Interleucina-1 / Reprogramación Celular Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article