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Discovery of InhA inhibitors with anti-mycobacterial activity through a matched molecular pair approach.
Kanetaka, Hironori; Koseki, Yuji; Taira, Junichi; Umei, Tomohiro; Komatsu, Hideyuki; Sakamoto, Hiroshi; Gulten, Gulcin; Sacchettini, James C; Kitamura, Mitsuru; Aoki, Shunsuke.
  • Kanetaka H; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka-shi, Fukuoka 820-8502, Japan.
  • Koseki Y; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka-shi, Fukuoka 820-8502, Japan.
  • Taira J; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka-shi, Fukuoka 820-8502, Japan.
  • Umei T; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka-shi, Fukuoka 820-8502, Japan.
  • Komatsu H; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka-shi, Fukuoka 820-8502, Japan.
  • Sakamoto H; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka-shi, Fukuoka 820-8502, Japan.
  • Gulten G; Department of Biochemistry & Biophysics, Texas A & M University, College Station, TX 77843-2128, United States.
  • Sacchettini JC; Department of Biochemistry & Biophysics, Texas A & M University, College Station, TX 77843-2128, United States.
  • Kitamura M; Department of Applied Chemistry, Kyushu Institute of Technology, 1-1 Sensui-cho, Tobata-ku, Kitakyushu-shi, Fukuoka 804-8550, Japan.
  • Aoki S; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka-shi, Fukuoka 820-8502, Japan; Biomedical Informatics Research and Development Center (BMIRC), Kyushu Institute of Technology, 680-4 Kawazu, I
Eur J Med Chem ; 94: 378-85, 2015 Apr 13.
Article en En | MEDLINE | ID: mdl-25778993

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oxidorreductasas / Proteínas Bacterianas / Mycobacterium smegmatis / Descubrimiento de Drogas / Antibacterianos Límite: Animals / Humans Idioma: En Año: 2015 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oxidorreductasas / Proteínas Bacterianas / Mycobacterium smegmatis / Descubrimiento de Drogas / Antibacterianos Límite: Animals / Humans Idioma: En Año: 2015 Tipo del documento: Article