Clinical bystander effect exerted by allergen immunotherapy: a hypothesis.
Eur Ann Allergy Clin Immunol
; 47(2): 62-3, 2015 Mar.
Article
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| MEDLINE
| ID: mdl-25781197
ABSTRACT
Allergen Immunotherapy (AIT) is able to restore a physiological Th1 response and Tregs function. This effect is allergen-specific, even though it has been reported that it may also be non-specific, such as also extended to allergens not used in AIT. This immunological phenomenon may also be of clinical nature. This case report shows that a poly-allergic patient, successfully treated with Parietaria extract, also achieved a clinical tolerance towards other causal allergens, such as mites and cat. Of course, this was an anecdote, but it is reasonable to prospect the hypothesis that a bystander clinical effect may be observed during AIT in poly-allergic patients.
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Banco de datos:
MEDLINE
Asunto principal:
Asma
/
Alérgenos
/
Rinitis Alérgica Perenne
/
Rinitis Alérgica Estacional
/
Desensibilización Inmunológica
/
Efecto Espectador
/
Parietaria
/
Antígenos de Plantas
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
/
Humans
/
Male
Idioma:
En
Año:
2015
Tipo del documento:
Article