FBXO4 loss facilitates carcinogen induced papilloma development in mice.

Lian, Zhaorui; Lee, Eric K; Bass, Adam J; Wong, Kwok K; Klein-Szanto, Andres Jp; Rustgi, Anil K; Diehl, J Alan

Lian, Zhaorui; Lee, Eric K; Bass, Adam J; Wong, Kwok K; Klein-Szanto, Andres Jp; Rustgi, Anil K; Diehl, J Alan.

Lian Z; a Institute for Regenerative Medicine; University of Pennsylvania School of Medicine ; Philadelphia , PA , USA.

Cancer Biol Ther ; 16(5): 750-5, 2015.

Article en En | MEDLINE | ID: mdl-25801820

Asunto(s)

Carcinoma de Células Escamosas/genética; Carcinoma de Células Escamosas/terapia; Ciclina D1/genética; Neoplasias Esofágicas/genética; Neoplasias Esofágicas/terapia; Proteínas F-Box/genética; Animales; Carcinoma de Células Escamosas/patología; Neoplasias Esofágicas/patología; Carcinoma de Células Escamosas de Esófago; Proteínas F-Box/metabolismo; Humanos; Ratones; Mutación

Palabras clave

BrdU, Bromodeoxyuridine; CDK, Cyclin Dependent Kinase; CDK4; DMSO, Dimethyl Sulfoxide; EGFR, Epidermal Growth Factor Receptor; ESCC; ESCC, Esophageal Squamous Cell Carcinoma; FBXO4; FBXO4, F box only protein 4; GI, Gastrointestinal tract; H&E, Hematoxylin and Eosin; Het, Heterozygous; NMBA, N-nitrosomethylbenzylamine; PBS, Phosphate Buffered Saline; PD0332991; PE, Preneoplastic Esophagus; PI, Propidium Iodide; Rb, Retinoblastoma Protein; SCC, Squamous Cell Carcinoma; SCF, Skp1-Cul1-F box protein; TNFa, Tumor Necrosis Factor alpha; Wt, Wild Type; cyclin D1

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Carcinoma de Células Escamosas / Ciclina D1 / Proteínas F-Box Límite: Animals / Humans Idioma: En Año: 2015 Tipo del documento: Article

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