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Fatty acid metabolism meets organelle dynamics.
Walch, Laurence; Copic, Alenka; Jackson, Catherine L.
  • Walch L; Institut Jacques Monod, CNRS, UMR 7592, Université Paris Diderot, Sorbonne Paris Cité, F-75013 Paris, France.
  • Copic A; Institut Jacques Monod, CNRS, UMR 7592, Université Paris Diderot, Sorbonne Paris Cité, F-75013 Paris, France.
  • Jackson CL; Institut Jacques Monod, CNRS, UMR 7592, Université Paris Diderot, Sorbonne Paris Cité, F-75013 Paris, France. Electronic address: jackson@ijm.univ-paris-diderot.fr.
Dev Cell ; 32(6): 657-8, 2015 Mar 23.
Article en En | MEDLINE | ID: mdl-25805129
ABSTRACT
Upon nutrient deprivation, cells metabolize fatty acids (FAs) in mitochondria to supply energy, but how FAs, stored as triacylglycerols in lipid droplets, reach mitochondria has been mysterious. Rambold et al. (2015) now show that FA mobilization depends on triacylglycerol lipolysis, whereas autophagy feeds the lipid droplet pool for continued fueling of mitochondria.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Autofagia / Inanición / Ácidos Grasos / Dinámicas Mitocondriales / Lipólisis Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Autofagia / Inanición / Ácidos Grasos / Dinámicas Mitocondriales / Lipólisis Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article