Providing an extended use of an otological-specific outcome instrument to derive cost-effectiveness estimates of treatment.
Clin Otolaryngol
; 40(6): 593-9, 2015 Dec.
Article
en En
| MEDLINE
| ID: mdl-25816901
ABSTRACT
OBJECTIVES:
Although quality-adjusted life years (QALYs) are increasingly being used by decision-makers to make comparisons of cost-effectiveness, there are no otological-specific outcome measures that fit within this QALY framework. This study had two main objectives. The first was to provide a means to derive QALYs from a condition-specific otological instrument (Cambridge Otology Quality of Life, COQOL), and the second was to assess the convergent validity, or degree of correlation, between the COQOL and SF-6D, an established QALY instrument.DESIGN:
Longitudinal cohort study designed to assess the convergent validity between SF-6D and COQOL and to generate a mapping function to enable SF-6D values to be predicted from the COQOL responses.SETTING:
Cambridge University Hospital, UK.PARTICIPANTS:
A total of 207 patients attending a routine outpatient general otology clinic. MAIN OUTCOMEMEASURES:
SF-6D and the COQOL instrument completed at baseline and again 3 months later.RESULTS:
Convergent validity was demonstrated with mean SF-6D values decreasing linearly with increasing severity on the COQOL instrument. Overall, the correlation between the COQOL scores and the SF-6D values was moderate and statistically significant (r = 0.490, P = <0.001). A simple mapping model based on an ordinary least squares (OLS) regression function predicted SF-6D values from the COQOL data with a reasonable degree of accuracy. Further validation using the follow-up 3-month data confirmed the prediction power of this mapping model.CONCLUSIONS:
This study provides a method for estimating QALYs from condition-specific COQOL data and provides the opportunity for the cost-effectiveness of otological treatment to be measured and placed within the national QALY framework.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Otolaringología
/
Psicometría
/
Calidad de Vida
/
Encuestas y Cuestionarios
/
Costo de Enfermedad
/
Toma de Decisiones
/
Enfermedades del Oído
Tipo de estudio:
Health_economic_evaluation
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
/
Middle aged
País como asunto:
Europa
Idioma:
En
Año:
2015
Tipo del documento:
Article