Secondary metabolites of plants from the genus chloranthus: chemistry and biological activities.
Chem Biodivers
; 12(4): 451-73, 2015 Apr.
Article
en En
| MEDLINE
| ID: mdl-25879494
ABSTRACT
Chloranthus, a genus of the family Chloranthaceae, which is mainly distributed in eastern and southern Asia, has been used in Chinese folk medicine due to its antitumor, antifungal, and anti-inflammatory activities. This review compiles the research on isolation, structure elucidation, structural diversity, and bioactivities of Chloranthus secondary metabolites reported between 2007 and 2013. The metabolites listed encompass 82 sesquiterpenoids, 50 dimeric sesquiterpenoids, 15 diterpenoids, one coumarin, and five other compounds. Among them, dimeric sesquiterpenoids, the characteristic components of plants from the genus Chloranthus, have attracted considerable attention due to their complex structures and significant biological features, e.g., antitumor, antibacterial, antifungal, anti-inflammatory, and hepatoprotective activities, and potent and selective inhibition of the delayed rectifier (IK) K(+) current and tyrosinase.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Antiinflamatorios no Esteroideos
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Magnoliopsida
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Antifúngicos
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Antineoplásicos Fitogénicos
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Año:
2015
Tipo del documento:
Article