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Constitutive activation of oncogenic PDGFRα-mutant proteins occurring in GIST patients induces receptor mislocalisation and alters PDGFRα signalling characteristics.
Bahlawane, Christelle; Eulenfeld, René; Wiesinger, Monique Y; Wang, Jiali; Muller, Arnaud; Girod, Andreas; Nazarov, Petr V; Felsch, Kathrin; Vallar, Laurent; Sauter, Thomas; Satagopam, Venkata P; Haan, Serge.
  • Bahlawane C; Molecular Disease Mechanisms Group, Life Sciences Research Unit, University of Luxembourg, 162A Avenue de la Faïencerie, L-1511, Luxembourg, Luxembourg. christelle.bahlawane@uni.lu.
  • Eulenfeld R; Signal Transduction Group, Life Sciences Research Unit, University of Luxembourg, 162A Avenue de la Faïencerie, L-1511, Luxembourg, Luxembourg. r_eule@gmx.de.
  • Wiesinger MY; Systems Biology Group, Life Sciences Research Unit, University of Luxembourg, 162A Avenue de la Faïencerie, L-1511, Luxembourg, Luxembourg. monique.wiesinger@uni.lu.
  • Wang J; Molecular Disease Mechanisms Group, Life Sciences Research Unit, University of Luxembourg, 162A Avenue de la Faïencerie, L-1511, Luxembourg, Luxembourg. jiali.wang@uni.lu.
  • Muller A; Genomics Research Unit, Luxembourg Institute of Health, 84 Val Fleuri, L-1526, Luxembourg, Luxembourg. Arnaud.Muller@lih.lu.
  • Girod A; Light Microscopy Facility, Life Sciences Research Unit, University of Luxembourg, 162a Avenue de la Faïencerie, L-1511, Luxembourg, Luxembourg. andreas.girod@uni.lu.
  • Nazarov PV; Genomics Research Unit, Luxembourg Institute of Health, 84 Val Fleuri, L-1526, Luxembourg, Luxembourg. Petr.Nazarov@lih.lu.
  • Felsch K; Deparment of Biochemistry, RWTH-Aachen University, Pauwelsstr. 30, D-52074, Aachen, Germany. Kathrin.Felsch@gmx.de.
  • Vallar L; Genomics Research Unit, Luxembourg Institute of Health, 84 Val Fleuri, L-1526, Luxembourg, Luxembourg. Laurent.Vallar@lih.lu.
  • Sauter T; Systems Biology Group, Life Sciences Research Unit, University of Luxembourg, 162A Avenue de la Faïencerie, L-1511, Luxembourg, Luxembourg. thomas.sauter@uni.lu.
  • Satagopam VP; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 7 Avenue des Hauts-Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg. venkata.satagopam@uni.lu.
  • Haan S; Molecular Disease Mechanisms Group, Life Sciences Research Unit, University of Luxembourg, 162A Avenue de la Faïencerie, L-1511, Luxembourg, Luxembourg. serge.haan@uni.lu.
Cell Commun Signal ; 13: 21, 2015 Mar 31.
Article en En | MEDLINE | ID: mdl-25880691
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Receptor alfa de Factor de Crecimiento Derivado de Plaquetas / Factores de Transcripción STAT / Neoplasias Gastrointestinales / Mutación / Proteínas de Neoplasias Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Receptor alfa de Factor de Crecimiento Derivado de Plaquetas / Factores de Transcripción STAT / Neoplasias Gastrointestinales / Mutación / Proteínas de Neoplasias Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article