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Trastuzumab Labeled to High Specific Activity with (111)In by Site-Specific Conjugation to a Metal-Chelating Polymer Exhibits Amplified Auger Electron-Mediated Cytotoxicity on HER2-Positive Breast Cancer Cells.
Ngo Ndjock Mbong, Ghislaine; Lu, Yijie; Chan, Conrad; Cai, Zhongli; Liu, Peng; Boyle, Amanda J; Winnik, Mitchell A; Reilly, Raymond M.
  • Ngo Ndjock Mbong G; †Department of Pharmaceutical Sciences, University of Toronto, 144 College Street, Toronto, ON M5S 3M2, Canada.
  • Lu Y; ‡Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON M5S 3H6, Canada.
  • Chan C; †Department of Pharmaceutical Sciences, University of Toronto, 144 College Street, Toronto, ON M5S 3M2, Canada.
  • Cai Z; †Department of Pharmaceutical Sciences, University of Toronto, 144 College Street, Toronto, ON M5S 3M2, Canada.
  • Liu P; ‡Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON M5S 3H6, Canada.
  • Boyle AJ; †Department of Pharmaceutical Sciences, University of Toronto, 144 College Street, Toronto, ON M5S 3M2, Canada.
  • Winnik MA; ‡Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON M5S 3H6, Canada.
  • Reilly RM; †Department of Pharmaceutical Sciences, University of Toronto, 144 College Street, Toronto, ON M5S 3M2, Canada.
Mol Pharm ; 12(6): 1951-60, 2015 Jun 01.
Article en En | MEDLINE | ID: mdl-25919639
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Polímeros / Radioisótopos de Indio / Receptor ErbB-2 / Trastuzumab Límite: Female / Humans Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Polímeros / Radioisótopos de Indio / Receptor ErbB-2 / Trastuzumab Límite: Female / Humans Idioma: En Año: 2015 Tipo del documento: Article