Actions of cAMP on calcium sensitization in human detrusor smooth muscle contraction.

Hayashi, Maya; Kajioka, Shunichi; Itsumi, Momoe; Takahashi, Ryosuke; Shahab, Nouval; Ishigami, Takao; Takeda, Masahiro; Masuda, Noriyuki; Yamaguchi, Akito; Naito, Seiji

Hayashi, Maya; Kajioka, Shunichi; Itsumi, Momoe; Takahashi, Ryosuke; Shahab, Nouval; Ishigami, Takao; Takeda, Masahiro; Masuda, Noriyuki; Yamaguchi, Akito; Naito, Seiji.

Hayashi M; Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka City, Japan.
Kajioka S; Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka City, Japan.
Itsumi M; Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka City, Japan.
Takahashi R; Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka City, Japan.
Shahab N; Department of Urology, Faculty of Medicine and Health Sciences, Syarif Hidayaullah Jakarta State Islamic University, Jakarta, Indonesia.
Ishigami T; Urology Research Unit, Drug Discovery Research, Astellas Pharma Inc., Tsukuba, Japan.
Takeda M; Urology Research Unit, Drug Discovery Research, Astellas Pharma Inc., Tsukuba, Japan.
Masuda N; Innovation and Research Portfolio Planning, Drug Discovery Research, Astellas Pharma Inc., Tsukuba, Japan.
Yamaguchi A; Division of Urology, Harasanshin Hospital, Fukuoka, Japan.
Naito S; Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka City, Japan.

BJU Int ; 117(1): 179-91, 2016 Jan.

Article en En | MEDLINE | ID: mdl-25981809

Asunto(s)

Calcio/metabolismo; AMP Cíclico/metabolismo; Contracción Muscular/fisiología; Músculo Liso/metabolismo; Vejiga Urinaria/metabolismo; Anciano; Señalización del Calcio/efectos de los fármacos; Señalización del Calcio/fisiología; AMP Cíclico/farmacología; Inhibidores Enzimáticos/farmacología; Femenino; Humanos; Masculino; Persona de Mediana Edad; Contracción Muscular/efectos de los fármacos; Músculo Liso/efectos de los fármacos; Músculo Liso/fisiología; Vejiga Urinaria/efectos de los fármacos; Vejiga Urinaria/fisiología

Palabras clave

cAMP; calcium sensitization; human detrusor smooth muscle; permeabilization; rho kinase; α-toxin

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vejiga Urinaria / Calcio / AMP Cíclico / Contracción Muscular / Músculo Liso Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2016 Tipo del documento: Article

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