Altered levels of mitochondrial DNA are associated with female age, aneuploidy, and provide an independent measure of embryonic implantation potential.

Fragouli, Elpida; Spath, Katharina; Alfarawati, Samer; Kaper, Fiona; Craig, Andrew; Michel, Claude-Edouard; Kokocinski, Felix; Cohen, Jacques; Munne, Santiago; Wells, Dagan

Fragouli, Elpida; Spath, Katharina; Alfarawati, Samer; Kaper, Fiona; Craig, Andrew; Michel, Claude-Edouard; Kokocinski, Felix; Cohen, Jacques; Munne, Santiago; Wells, Dagan.

Fragouli E; Reprogenetics UK, Oxford, United Kingdom.
Spath K; Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom.
Alfarawati S; Reprogenetics UK, Oxford, United Kingdom.
Kaper F; Illumina, San Diego, California, United States of America.
Craig A; Illumina, Cambridge, United Kingdom.
Michel CE; Illumina, Cambridge, United Kingdom.
Kokocinski F; Illumina, Cambridge, United Kingdom.
Cohen J; Reprogenetics LLC, Livingston, New Jersey, United States of America.
Munne S; Reprogenetics LLC, Livingston, New Jersey, United States of America.
Wells D; Reprogenetics UK, Oxford, United Kingdom; Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom.

PLoS Genet ; 11(6): e1005241, 2015 Jun.

Article en En | MEDLINE | ID: mdl-26039092

Asunto(s)

Aneuploidia; ADN Mitocondrial/genética; Implantación del Embrión/genética; Adulto; Factores de Edad; Femenino; Humanos

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Implantación del Embrión / ADN Mitocondrial / Aneuploidia Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans Idioma: En Año: 2015 Tipo del documento: Article

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