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[Curare-Like Camphor Derivatives and Their Biological Activity].
Bioorg Khim ; 41(2): 203-11, 2015.
Article en Ru | MEDLINE | ID: mdl-26165127
The synthesis and evaluation of muscle relaxant activity of series of dimeric camphor derivatives are described. Compounds in which the quaternary nitrogen atoms are separated by aromatic chain exhibited the highest efficiency as muscle relaxant. It was shown the screening of a charged atom and counter-ion does not have a significant role on the activity of the studied agents.
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Banco de datos: MEDLINE Asunto principal: Alcanfor / Fármacos Neuromusculares no Despolarizantes Límite: Animals Idioma: Ru Año: 2015 Tipo del documento: Article
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Banco de datos: MEDLINE Asunto principal: Alcanfor / Fármacos Neuromusculares no Despolarizantes Límite: Animals Idioma: Ru Año: 2015 Tipo del documento: Article