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Blockade of the PD-1/PD-L1 axis augments lysis of AML cells by the CD33/CD3 BiTE antibody construct AMG 330: reversing a T-cell-induced immune escape mechanism.
Krupka, C; Kufer, P; Kischel, R; Zugmaier, G; Lichtenegger, F S; Köhnke, T; Vick, B; Jeremias, I; Metzeler, K H; Altmann, T; Schneider, S; Fiegl, M; Spiekermann, K; Bauerle, P A; Hiddemann, W; Riethmüller, G; Subklewe, M.
  • Krupka C; Department of Internal Medicine III, LMU-Klinikum der Universität München, Munich, Germany.
  • Kufer P; Clinical Co-operation Group Immunotherapy at the Helmholtz Zentrum München, Munich, Germany.
  • Kischel R; AMGEN Research (Munich) GmbH, Munich, Germany.
  • Zugmaier G; AMGEN Research (Munich) GmbH, Munich, Germany.
  • Lichtenegger FS; AMGEN Research (Munich) GmbH, Munich, Germany.
  • Köhnke T; Department of Internal Medicine III, LMU-Klinikum der Universität München, Munich, Germany.
  • Vick B; Clinical Co-operation Group Immunotherapy at the Helmholtz Zentrum München, Munich, Germany.
  • Jeremias I; Department of Internal Medicine III, LMU-Klinikum der Universität München, Munich, Germany.
  • Metzeler KH; Clinical Co-operation Group Immunotherapy at the Helmholtz Zentrum München, Munich, Germany.
  • Altmann T; Department of Gene Vectors, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.
  • Schneider S; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Fiegl M; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Spiekermann K; Department of Gene Vectors, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.
  • Bauerle PA; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Hiddemann W; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Riethmüller G; Department of Oncology, Dr von Haunersches Kinderspital, Ludwig Maximilians-Universität (LMU), Munich, Germany.
  • Subklewe M; Department of Internal Medicine III, LMU-Klinikum der Universität München, Munich, Germany.
Leukemia ; 30(2): 484-91, 2016 Feb.
Article en En | MEDLINE | ID: mdl-26239198
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T / Leucemia Mieloide Aguda / Anticuerpos Biespecíficos / Escape del Tumor / Antígeno B7-H1 / Receptor de Muerte Celular Programada 1 Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T / Leucemia Mieloide Aguda / Anticuerpos Biespecíficos / Escape del Tumor / Antígeno B7-H1 / Receptor de Muerte Celular Programada 1 Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article