Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NF&#954;B Activity in Macrophages.

Hamers, Anouk A J; van Dam, Laura; Teixeira Duarte, José M; Vos, Mariska; Marinkovic, Goran; van Tiel, Claudia M; Meijer, Sybren L; van Stalborch, Anne-Marieke; Huveneers, Stephan; Te Velde, Anje A; de Jonge, Wouter J; de Vries, Carlie J M

Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages.

Hamers, Anouk A J; van Dam, Laura; Teixeira Duarte, José M; Vos, Mariska; Marinkovic, Goran; van Tiel, Claudia M; Meijer, Sybren L; van Stalborch, Anne-Marieke; Huveneers, Stephan; Te Velde, Anje A; de Jonge, Wouter J; de Vries, Carlie J M.

Hamers AA; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
van Dam L; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Teixeira Duarte JM; Tytgat Institute, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Vos M; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Marinkovic G; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
van Tiel CM; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Meijer SL; Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
van Stalborch AM; Department of Molecular Cell Biology, Sanquin Research and Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands.
Huveneers S; Department of Molecular Cell Biology, Sanquin Research and Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands.
Te Velde AA; Tytgat Institute, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
de Jonge WJ; Tytgat Institute, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
de Vries CJ; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

PLoS One ; 10(8): e0133598, 2015.

Article en En | MEDLINE | ID: mdl-26241646

Asunto(s)

Colitis Ulcerosa/metabolismo; Colitis/metabolismo; Enfermedad de Crohn/metabolismo; Macrófagos/metabolismo; FN-kappa B/metabolismo; Miembro 1 del Grupo A de la Subfamilia 4 de Receptores Nucleares/inmunología; Animales; Línea Celular; Colitis/inducido químicamente; Colitis/inmunología; Colitis Ulcerosa/patología; Colon/metabolismo; Colon/patología; Enfermedad de Crohn/patología; Citocinas/biosíntesis; Citocinas/genética; Sulfato de Dextran/toxicidad; Modelos Animales de Enfermedad; Células Epiteliales/metabolismo; Células Epiteliales/patología; Femenino; Factores de Transcripción Forkhead/biosíntesis; Factores de Transcripción Forkhead/genética; Regulación de la Expresión Génica; Humanos; Mucosa Intestinal/metabolismo; Mucosa Intestinal/patología; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Miembro 1 del Grupo A de la Subfamilia 4 de Receptores Nucleares/deficiencia; Miembro 1 del Grupo A de la Subfamilia 4 de Receptores Nucleares/genética; Células RAW 264.7; Ácido Trinitrobencenosulfónico/toxicidad

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Enfermedad de Crohn / FN-kappa B / Colitis / Miembro 1 del Grupo A de la Subfamilia 4 de Receptores Nucleares / Macrófagos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2015 Tipo del documento: Article

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