The angiogenic responses induced by release of angiogenic proteins from tumor cell-activated platelets are regulated by distinct molecular pathways.

Wu, Hongyan; Fan, Fangtian; Liu, Zhaoguo; Zhang, Feng; Liu, Yuping; Wei, Zhonghong; Shen, Cunsi; Cao, Yuzhu; Wang, Aiyun; Lu, Yin

Wu, Hongyan; Fan, Fangtian; Liu, Zhaoguo; Zhang, Feng; Liu, Yuping; Wei, Zhonghong; Shen, Cunsi; Cao, Yuzhu; Wang, Aiyun; Lu, Yin.

Wu H; Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Fan F; Department of Pharmacy, Yancheng Health Vocational and Technical College, Yancheng, China.
Liu Z; Department of Pharmacology, Hanlin College, Nanjing University of Chinese Medicine, Taizhou, China.
Zhang F; Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Liu Y; Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Wei Z; Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Shen C; Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Cao Y; First School of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Wang A; Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Lu Y; Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.

IUBMB Life ; 67(8): 626-33, 2015 Aug.

Article en En | MEDLINE | ID: mdl-26283102

Asunto(s)

Plaquetas/metabolismo; Carcinoma de Pulmón de Células no Pequeñas/genética; Neovascularización Patológica; Trombocitosis/genética; Coagulación Sanguínea/genética; Carcinoma de Pulmón de Células no Pequeñas/metabolismo; Carcinoma de Pulmón de Células no Pequeñas/patología; Línea Celular Tumoral; Movimiento Celular; Citocinas/metabolismo; Células Endoteliales de la Vena Umbilical Humana; Humanos; Activación Plaquetaria/genética; Transducción de Señal/genética; Trombocitosis/metabolismo; Trombocitosis/patología; Factor A de Crecimiento Endotelial Vascular/genética; Factor A de Crecimiento Endotelial Vascular/metabolismo

Palabras clave

COX-1; NSCLC; P2Y12; integrin αIIbß3; platelet secretion; tumor angiogenesis

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trombocitosis / Plaquetas / Carcinoma de Pulmón de Células no Pequeñas / Neovascularización Patológica Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article

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