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A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates.
Muthumani, Karuppiah; Falzarano, Darryl; Reuschel, Emma L; Tingey, Colleen; Flingai, Seleeke; Villarreal, Daniel O; Wise, Megan; Patel, Ami; Izmirly, Abdullah; Aljuaid, Abdulelah; Seliga, Alecia M; Soule, Geoff; Morrow, Matthew; Kraynyak, Kimberly A; Khan, Amir S; Scott, Dana P; Feldmann, Friederike; LaCasse, Rachel; Meade-White, Kimberly; Okumura, Atsushi; Ugen, Kenneth E; Sardesai, Niranjan Y; Kim, J Joseph; Kobinger, Gary; Feldmann, Heinz; Weiner, David B.
  • Muthumani K; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.
  • Falzarano D; Laboratory of Virology, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Hamilton, MT 59840, USA.
  • Reuschel EL; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.
  • Tingey C; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.
  • Flingai S; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.
  • Villarreal DO; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.
  • Wise M; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.
  • Patel A; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.
  • Izmirly A; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.
  • Aljuaid A; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.
  • Seliga AM; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.
  • Soule G; Special Pathogens Program, University of Manitoba and Public Health Agency of Canada, Winnipeg, Manitoba R3E 3R2, Canada.
  • Morrow M; Inovio Pharmaceuticals Inc., Plymouth Meeting, PA 19462, USA.
  • Kraynyak KA; Inovio Pharmaceuticals Inc., Plymouth Meeting, PA 19462, USA.
  • Khan AS; Inovio Pharmaceuticals Inc., Plymouth Meeting, PA 19462, USA.
  • Scott DP; Rocky Mountain Veterinary Branch, Division of Intramural Research, NIAID, NIH, Hamilton, MT 59840, USA.
  • Feldmann F; Rocky Mountain Veterinary Branch, Division of Intramural Research, NIAID, NIH, Hamilton, MT 59840, USA.
  • LaCasse R; Rocky Mountain Veterinary Branch, Division of Intramural Research, NIAID, NIH, Hamilton, MT 59840, USA.
  • Meade-White K; Rocky Mountain Veterinary Branch, Division of Intramural Research, NIAID, NIH, Hamilton, MT 59840, USA.
  • Okumura A; Department of Microbiology, University of Washington, Seattle, WA 98195, USA.
  • Ugen KE; Department of Molecular Medicine, University of South Florida Morsani College of Medicine, Tampa, FL 33612, USA.
  • Sardesai NY; Inovio Pharmaceuticals Inc., Plymouth Meeting, PA 19462, USA.
  • Kim JJ; Inovio Pharmaceuticals Inc., Plymouth Meeting, PA 19462, USA.
  • Kobinger G; Special Pathogens Program, University of Manitoba and Public Health Agency of Canada, Winnipeg, Manitoba R3E 3R2, Canada.
  • Feldmann H; Laboratory of Virology, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Hamilton, MT 59840, USA.
  • Weiner DB; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA. dbweiner@mail.med.upenn.edu.
Sci Transl Med ; 7(301): 301ra132, 2015 Aug 19.
Article en En | MEDLINE | ID: mdl-26290414
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vacunas de ADN / Coronavirus del Síndrome Respiratorio de Oriente Medio Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vacunas de ADN / Coronavirus del Síndrome Respiratorio de Oriente Medio Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article