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Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor.
Gornalusse, German G; Mummidi, Srinivas; Gaitan, Alvaro A; Jimenez, Fabio; Ramsuran, Veron; Picton, Anabela; Rogers, Kristen; Manoharan, Muthu Saravanan; Avadhanam, Nymisha; Murthy, Krishna K; Martinez, Hernan; Molano Murillo, Angela; Chykarenko, Zoya A; Hutt, Richard; Daskalakis, Demetre; Shostakovich-Koretskaya, Ludmila; Abdool Karim, Salim; Martin, Jeffrey N; Deeks, Steven G; Hecht, Frederick; Sinclair, Elizabeth; Clark, Robert A; Okulicz, Jason; Valentine, Fred T; Martinson, Neil; Tiemessen, Caroline Tanya; Ndung'u, Thumbi; Hunt, Peter W; He, Weijing; Ahuja, Sunil K.
  • Gornalusse GG; Veterans Administration Research Center for AIDS and HIV-1 Infection, South Texas Veterans Health Care System, San Antonio, TX 78229; Center for Personalized Medicine, South Texas Veterans Health Care System, San Antonio, TX 78229; Department of Medicine, University of Texas Health Science Center, S
  • Mummidi S; Veterans Administration Research Center for AIDS and HIV-1 Infection, South Texas Veterans Health Care System, San Antonio, TX 78229; Center for Personalized Medicine, South Texas Veterans Health Care System, San Antonio, TX 78229; Department of Medicine, University of Texas Health Science Center, S
  • Gaitan AA; Veterans Administration Research Center for AIDS and HIV-1 Infection, South Texas Veterans Health Care System, San Antonio, TX 78229; Center for Personalized Medicine, South Texas Veterans Health Care System, San Antonio, TX 78229; Department of Medicine, University of Texas Health Science Center, S
  • Jimenez F; Veterans Administration Research Center for AIDS and HIV-1 Infection, South Texas Veterans Health Care System, San Antonio, TX 78229; Center for Personalized Medicine, South Texas Veterans Health Care System, San Antonio, TX 78229; Department of Medicine, University of Texas Health Science Center, S
  • Ramsuran V; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban 4013, South Africa; Centre for the AIDS Program of Research in South Africa (CAPRISA), Doris Duke Medical Research Institute, Nelson R Mandela School of Medicin
  • Picton A; Centre for HIV and Sexually Transmitted Infections, National Institute for Communicable Diseases, Sandringham, Johannesburg 2131, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa;
  • Rogers K; Veterans Administration Research Center for AIDS and HIV-1 Infection, South Texas Veterans Health Care System, San Antonio, TX 78229; Center for Personalized Medicine, South Texas Veterans Health Care System, San Antonio, TX 78229; Department of Medicine, University of Texas Health Science Center, S
  • Manoharan MS; Veterans Administration Research Center for AIDS and HIV-1 Infection, South Texas Veterans Health Care System, San Antonio, TX 78229; Center for Personalized Medicine, South Texas Veterans Health Care System, San Antonio, TX 78229; Department of Medicine, University of Texas Health Science Center, S
  • Avadhanam N; Veterans Administration Research Center for AIDS and HIV-1 Infection, South Texas Veterans Health Care System, San Antonio, TX 78229; Center for Personalized Medicine, South Texas Veterans Health Care System, San Antonio, TX 78229; Department of Medicine, University of Texas Health Science Center, S
  • Murthy KK; Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, TX 78245;
  • Martinez H; Veterans Administration Research Center for AIDS and HIV-1 Infection, South Texas Veterans Health Care System, San Antonio, TX 78229; Center for Personalized Medicine, South Texas Veterans Health Care System, San Antonio, TX 78229; Department of Medicine, University of Texas Health Science Center, S
  • Molano Murillo A; Veterans Administration Research Center for AIDS and HIV-1 Infection, South Texas Veterans Health Care System, San Antonio, TX 78229; Center for Personalized Medicine, South Texas Veterans Health Care System, San Antonio, TX 78229; Department of Medicine, University of Texas Health Science Center, S
  • Chykarenko ZA; Department of General Pediatrics and Pediatric Infectious Diseases, Dnepropetrovsk State Medical Academy, 49044 Dnepropetrovsk, Ukraine;
  • Hutt R; Department of Medicine, New York University School of Medicine, New York, NY 10016;
  • Daskalakis D; Department of Medicine, New York University School of Medicine, New York, NY 10016;
  • Shostakovich-Koretskaya L; Department of General Pediatrics and Pediatric Infectious Diseases, Dnepropetrovsk State Medical Academy, 49044 Dnepropetrovsk, Ukraine;
  • Abdool Karim S; Centre for the AIDS Program of Research in South Africa (CAPRISA), Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban 4013, South Africa;
  • Martin JN; Department of Medicine, University of California, San Francisco, CA 94110; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94110; San Francisco General Hospital, San Francisco, CA 94110;
  • Deeks SG; Department of Medicine, University of California, San Francisco, CA 94110; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94110; San Francisco General Hospital, San Francisco, CA 94110;
  • Hecht F; Department of Medicine, University of California, San Francisco, CA 94110; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94110; San Francisco General Hospital, San Francisco, CA 94110;
  • Sinclair E; Department of Medicine, University of California, San Francisco, CA 94110; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94110; San Francisco General Hospital, San Francisco, CA 94110;
  • Clark RA; Veterans Administration Research Center for AIDS and HIV-1 Infection, South Texas Veterans Health Care System, San Antonio, TX 78229; Center for Personalized Medicine, South Texas Veterans Health Care System, San Antonio, TX 78229; Department of Medicine, University of Texas Health Science Center, S
  • Okulicz J; San Antonio Military Medical Center, Fort Sam Houston, San Antonio, TX 78234;
  • Valentine FT; Department of Medicine, New York University School of Medicine, New York, NY 10016;
  • Martinson N; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa; Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg 2193, South Africa; Medical Research Council Soweto Matlosana Centre for HIV/AIDS and Tuberculosis, Johannesburg 2193, South Africa
  • Tiemessen CT; Centre for HIV and Sexually Transmitted Infections, National Institute for Communicable Diseases, Sandringham, Johannesburg 2131, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa; Medical Research Council Soweto Matlosana Centre for HIV/AIDS
  • Ndung'u T; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban 4013, South Africa; Centre for the AIDS Program of Research in South Africa (CAPRISA), Doris Duke Medical Research Institute, Nelson R Mandela School of Medicin
  • Hunt PW; Department of Medicine, University of California, San Francisco, CA 94110; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94110; San Francisco General Hospital, San Francisco, CA 94110;
  • He W; Veterans Administration Research Center for AIDS and HIV-1 Infection, South Texas Veterans Health Care System, San Antonio, TX 78229; Center for Personalized Medicine, South Texas Veterans Health Care System, San Antonio, TX 78229; Department of Medicine, University of Texas Health Science Center, S
  • Ahuja SK; Veterans Administration Research Center for AIDS and HIV-1 Infection, South Texas Veterans Health Care System, San Antonio, TX 78229; Center for Personalized Medicine, South Texas Veterans Health Care System, San Antonio, TX 78229; Department of Medicine, University of Texas Health Science Center, S
Proc Natl Acad Sci U S A ; 112(34): E4762-71, 2015 Aug 25.
Article en En | MEDLINE | ID: mdl-26307764
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores Virales / Activación de Linfocitos / Linfocitos T / VIH-1 / Receptores CCR5 / Epigénesis Genética Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores Virales / Activación de Linfocitos / Linfocitos T / VIH-1 / Receptores CCR5 / Epigénesis Genética Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article