Biased signalling: the instinctive skill of the cell in the selection of appropriate signalling pathways.

Liu, Ying; Yang, Yang; Ward, Richard; An, Su; Guo, Xiao-Xi; Li, Wei; Xu, Tian-Rui

Liu, Ying; Yang, Yang; Ward, Richard; An, Su; Guo, Xiao-Xi; Li, Wei; Xu, Tian-Rui.

Liu Y; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, 650500, China.
Yang Y; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, 650500, China.
Ward R; Molecular Pharmacology Group, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, Scotland, U.K.
An S; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, 650500, China.
Guo XX; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, 650500, China.
Li W; Department of Urology, the People's Hospital of Yunnan Province, Kunming, Yunnan, 650032, China lw13908701155@163.com xtrgfq@homail.com.
Xu TR; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, 650500, China lw13908701155@163.com xtrgfq@homail.com.

Biochem J ; 470(2): 155-67, 2015 Sep 01.

Article en En | MEDLINE | ID: mdl-26348905

Asunto(s)

Receptores Odorantes/metabolismo; Transducción de Señal; Animales; Arrestinas/metabolismo; Proteínas de Unión al GTP/metabolismo; Humanos; Ligandos; Conformación Proteica; Receptores Odorantes/química; beta-Arrestinas

Palabras clave

G-protein-coupled receptors (GPCRs); biased signalling; drug discovery; ligands; ß-arrestin

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Receptores Odorantes Límite: Animals / Humans Idioma: En Año: 2015 Tipo del documento: Article

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