Merosesquiterpenoids and ten-membered macrolides from a soft coral-derived Lophiostoma sp. fungus.
Chem Biodivers
; 12(9): 1407-14, 2015 Sep.
Article
en En
| MEDLINE
| ID: mdl-26363884
ABSTRACT
One new merosesquiterpenoid, craterellin D (1), along with one known analog, craterellin A (2), and five known ten-membered macrolides, 3-7, were isolated from a soft coral-derived Lophiostoma sp. fungus. The absolute configuration of 1 was established based on biogenetic consideration with the co-isolated analog 2, whose configuration was determined by modified Mosher's method and single-crystal X-ray diffraction analysis using CuKα radiation. The absolute configuration of 3 was determined by X-ray diffraction analysis using CuKα radiation. Compounds 2 and 3 showed antibacterial activities against Bacillus cereus with a MIC value of 3.12â
µM.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Ascomicetos
/
Sesquiterpenos
/
Macrólidos
/
Antozoos
/
Antibacterianos
Límite:
Animals
Idioma:
En
Año:
2015
Tipo del documento:
Article