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Design, synthesis and biological evaluation of novel pyrazolo-pyrimidinones as DPP-IV inhibitors in diabetes.
Sagar, Sneha R; Agarwal, Jessica K; Pandya, Dhaivat H; Dash, Ranjeet Prasad; Nivsarkar, Manish; Vasu, Kamala K.
  • Sagar SR; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research-Ahmedabad, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India; Department of Medicinal Chemistry, B. V. Patel Pharmaceutical Education and Research Development (PERD) Centre, S. G. Highway, Thaltej,
  • Agarwal JK; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research-Ahmedabad, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India.
  • Pandya DH; Department of Medicinal Chemistry, B. V. Patel Pharmaceutical Education and Research Development (PERD) Centre, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India.
  • Dash RP; Department of Pharmacology and Toxicology, B. V. Patel Pharmaceutical Education and Research Development (PERD) Centre, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India.
  • Nivsarkar M; Department of Pharmacology and Toxicology, B. V. Patel Pharmaceutical Education and Research Development (PERD) Centre, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India.
  • Vasu KK; Department of Medicinal Chemistry, B. V. Patel Pharmaceutical Education and Research Development (PERD) Centre, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India. Electronic address: kamalav@perdcentre.com.
Bioorg Med Chem Lett ; 25(20): 4428-33, 2015 Oct 15.
Article en En | MEDLINE | ID: mdl-26372650
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinonas / Diseño de Fármacos / Dipeptidil Peptidasa 4 / Diabetes Mellitus Experimental / Hipoglucemiantes Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinonas / Diseño de Fármacos / Dipeptidil Peptidasa 4 / Diabetes Mellitus Experimental / Hipoglucemiantes Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article