First report of somatic mosaicism for mutations in STK11 in four patients with Peutz-Jeghers syndrome.

McKay, Victoria; Cairns, Diane; Gokhale, David; Mountford, Roger; Greenhalgh, Lynn

McKay, Victoria; Cairns, Diane; Gokhale, David; Mountford, Roger; Greenhalgh, Lynn.

McKay V; Department of Clinical Genetics, Merseyside and Cheshire Regional Clinical Genetics Service, Liverpool Women's NHS Foundation Trust, Crown Street, Liverpool, L8 7SS, UK. Victoria.mckay@lwh.nhs.uk.
Cairns D; Merseyside and Cheshire Regional Molecular Genetics Laboratory, Liverpool Women's NHS Foundation Trust, Crown Street, Liverpool, L8 7SS, UK.
Gokhale D; Merseyside and Cheshire Regional Molecular Genetics Laboratory, Liverpool Women's NHS Foundation Trust, Crown Street, Liverpool, L8 7SS, UK.
Mountford R; Merseyside and Cheshire Regional Molecular Genetics Laboratory, Liverpool Women's NHS Foundation Trust, Crown Street, Liverpool, L8 7SS, UK.
Greenhalgh L; Department of Clinical Genetics, Merseyside and Cheshire Regional Clinical Genetics Service, Liverpool Women's NHS Foundation Trust, Crown Street, Liverpool, L8 7SS, UK.

Fam Cancer ; 15(1): 57-61, 2016 Jan.

Article en En | MEDLINE | ID: mdl-26386697

Asunto(s)

Síndrome de Peutz-Jeghers/genética; Proteínas Serina-Treonina Quinasas/genética; Quinasas de la Proteína-Quinasa Activada por el AMP; Femenino; Humanos; Masculino; Mosaicismo; Reacción en Cadena de la Polimerasa Multiplex; Mutación

Palabras clave

Deletion; LKB1; PeutzJeghers syndrome; STK11; Somatic mosaicism

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Síndrome de Peutz-Jeghers / Proteínas Serina-Treonina Quinasas Límite: Female / Humans / Male Idioma: En Año: 2016 Tipo del documento: Article

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