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Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.
Wiesner, Thomas; Lee, William; Obenauf, Anna C; Ran, Leili; Murali, Rajmohan; Zhang, Qi Fan; Wong, Elissa W P; Hu, Wenhuo; Scott, Sasinya N; Shah, Ronak H; Landa, Iñigo; Button, Julia; Lailler, Nathalie; Sboner, Andrea; Gao, Dong; Murphy, Devan A; Cao, Zhen; Shukla, Shipra; Hollmann, Travis J; Wang, Lu; Borsu, Laetitia; Merghoub, Taha; Schwartz, Gary K; Postow, Michael A; Ariyan, Charlotte E; Fagin, James A; Zheng, Deyou; Ladanyi, Marc; Busam, Klaus J; Berger, Michael F; Chen, Yu; Chi, Ping.
  • Wiesner T; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Lee W; Department of Dermatology, Medical University of Graz, 8010 Graz, Austria.
  • Obenauf AC; Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Ran L; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Murali R; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Zhang QF; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Wong EW; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Hu W; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Scott SN; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Shah RH; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Landa I; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Button J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Lailler N; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Sboner A; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Gao D; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Murphy DA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Cao Z; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Shukla S; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Hollmann TJ; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College/New York Presbyterian Hospital, New York 10065, USA.
  • Wang L; Institute for Computational Biomedicine, Weill Cornell Medical College/New York Presbyterian Hospital, New York 10065, USA.
  • Borsu L; Institute for Precision Medicine, Weill Cornell Medical College/New York Presbyterian Hospital, New York, USA.
  • Merghoub T; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Schwartz GK; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Postow MA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Ariyan CE; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Fagin JA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Zheng D; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Ladanyi M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Busam KJ; Immunology Program, Memorial Sloan Kettering Cancer Center 10065, New York, USA.
  • Berger MF; Herbert Irving Comprehensive Cancer Center, Columbia University Cancer Center, New York 10032, USA.
  • Chen Y; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York 10065, USA.
  • Chi P; Department of Medicine, Weill Cornell Medical College, New York 10065, USA.
Nature ; 526(7573): 453-7, 2015 Oct 15.
Article en En | MEDLINE | ID: mdl-26444240
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Regulación Neoplásica de la Expresión Génica / Proteínas Tirosina Quinasas Receptoras / Iniciación de la Transcripción Genética / Neoplasias Tipo de estudio: Prognostic_studies Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Regulación Neoplásica de la Expresión Génica / Proteínas Tirosina Quinasas Receptoras / Iniciación de la Transcripción Genética / Neoplasias Tipo de estudio: Prognostic_studies Idioma: En Año: 2015 Tipo del documento: Article