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Tuberculosis: pH-Responsive Isoniazid-Loaded Nanoparticles Markedly Improve Tuberculosis Treatment in Mice (Small 38/2015).
Hwang, Angela A; Lee, Bai-Yu; Clemens, Daniel L; Dillon, Barbara Jane; Zink, Jeffrey I; Horwitz, Marcus A.
  • Hwang AA; Department of Chemistry and Biochemistry, University of California, Los Angeles, 3013 Young Dr. East, CA, 90095-1569, USA.
  • Lee BY; Division of Infectious Diseases, Department of Medicine, University of California, Los Angeles, CHS 37-121, 10833 Le Conte Ave., CA, 90095-1688, USA.
  • Clemens DL; Division of Infectious Diseases, Department of Medicine, University of California, Los Angeles, CHS 37-121, 10833 Le Conte Ave., CA, 90095-1688, USA.
  • Dillon BJ; Division of Infectious Diseases, Department of Medicine, University of California, Los Angeles, CHS 37-121, 10833 Le Conte Ave., CA, 90095-1688, USA.
  • Zink JI; Department of Chemistry and Biochemistry, University of California, Los Angeles, 3013 Young Dr. East, CA, 90095-1569, USA.
  • Horwitz MA; California NanoSystems Institute, University of California, Los Angeles, CA, 90095-8352, USA.
Small ; 11(38): 5065, 2015 Oct.
Article en En | MEDLINE | ID: mdl-26450161
ABSTRACT
On page 5066, J. I. Zink, M. A. Horwitz, and co-workers use confocal microscopy to demonstrate the avid uptake of RITC-labeled mesoporous silica nanoparticles loaded with the anti-tuberculosis drug isoniazid (shown here in red) by human macrophages (nuclei stained blue with DAPI) infected with GFP-expressing Mycobacterium tuberculosis (shown here in green).
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tuberculosis / Nanopartículas / Isoniazida Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tuberculosis / Nanopartículas / Isoniazida Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article