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Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis.
Tew, Gaik W; Hackney, Jason A; Gibbons, Deena; Lamb, Christopher A; Luca, Diana; Egen, Jackson G; Diehl, Lauri; Eastham Anderson, Jeff; Vermeire, Severine; Mansfield, John C; Feagan, Brian G; Panes, Julian; Baumgart, Daniel C; Schreiber, Stefan; Dotan, Iris; Sandborn, William J; Kirby, John A; Irving, Peter M; De Hertogh, Gert; Van Assche, Gert A; Rutgeerts, Paul; O'Byrne, Sharon; Hayday, Adrian; Keir, Mary E.
  • Tew GW; Genentech Research and Early Development, South San Francisco, California.
  • Hackney JA; Genentech Research and Early Development, South San Francisco, California.
  • Gibbons D; King's College, London, United Kingdom.
  • Lamb CA; Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Luca D; Genentech Research and Early Development, South San Francisco, California.
  • Egen JG; Genentech Research and Early Development, South San Francisco, California.
  • Diehl L; Genentech Research and Early Development, South San Francisco, California.
  • Eastham Anderson J; Genentech Research and Early Development, South San Francisco, California.
  • Vermeire S; University of Leuven, Leuven, Belgium.
  • Mansfield JC; Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Feagan BG; University of Western Ontario, London, Ontario, Canada.
  • Panes J; Hospital Clinic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Barcelona, Spain.
  • Baumgart DC; Charité Medical School, Humboldt-University of Berlin, Germany.
  • Schreiber S; Department of Medicine I, University Hospital Schleswig-Holstein, Christian Albrechts University, Kiel, Germany.
  • Dotan I; Inflammatory Bowel Disease Center, Department of Gastroenterology and Liver Diseases, Tel Aviv Medical Center and Sackler Faculty of Medicine, Tel Aviv, Israel.
  • Sandborn WJ; University of California San Diego, La Jolla, California.
  • Kirby JA; Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Irving PM; King's College, London, United Kingdom.
  • De Hertogh G; University of Leuven, Leuven, Belgium.
  • Van Assche GA; University of Leuven, Leuven, Belgium; University of Toronto, Toronto, Ontario, Canada.
  • Rutgeerts P; University of Leuven, Leuven, Belgium.
  • O'Byrne S; Genentech Research and Early Development, South San Francisco, California.
  • Hayday A; King's College, London, United Kingdom.
  • Keir ME; Genentech Research and Early Development, South San Francisco, California. Electronic address: keir.mary@gene.com.
Gastroenterology ; 150(2): 477-87.e9, 2016 Feb.
Article en En | MEDLINE | ID: mdl-26522261
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Texto completo: 1 Ejes tematicos: Pesquisa_clinica Banco de datos: MEDLINE Asunto principal: Fármacos Gastrointestinales / Colitis Ulcerosa / Antígenos CD / Colon / Cadenas alfa de Integrinas / Granzimas / Anticuerpos Monoclonales Humanizados / Antiinflamatorios Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Ejes tematicos: Pesquisa_clinica Banco de datos: MEDLINE Asunto principal: Fármacos Gastrointestinales / Colitis Ulcerosa / Antígenos CD / Colon / Cadenas alfa de Integrinas / Granzimas / Anticuerpos Monoclonales Humanizados / Antiinflamatorios Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article