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Design, synthesis and antithrombotic evaluation of novel dabigatran etexilate analogs, a new series of non-peptides thrombin inhibitors.
Chen, Dongxing; Wang, Shaochi; Diao, Xiaojuan; Zhu, Qihua; Shen, Huiliang; Han, Xueqing; Wang, Yiwei; Gong, Guoqing; Xu, Yungen.
  • Chen D; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 21009, China.
  • Wang S; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 21009, China.
  • Diao X; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 21009, China; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 21009, China.
  • Zhu Q; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 21009, China; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 21009, China.
  • Shen H; Department of Pharmacology, China Pharmaceutical University, Nanjing 21009, China.
  • Han X; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 21009, China; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 21009, China.
  • Wang Y; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 21009, China; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 21009, China.
  • Gong G; Department of Pharmacology, China Pharmaceutical University, Nanjing 21009, China.
  • Xu Y; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 21009, China; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 21009, China. Electronic address: xu_yungen@hotmail.com.
Bioorg Med Chem ; 23(23): 7405-16, 2015 Dec 01.
Article en En | MEDLINE | ID: mdl-26537784
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Inhibidores de Agregación Plaquetaria / Trombina / Dabigatrán / Anticoagulantes Límite: Animals / Humans / Male Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Inhibidores de Agregación Plaquetaria / Trombina / Dabigatrán / Anticoagulantes Límite: Animals / Humans / Male Idioma: En Año: 2015 Tipo del documento: Article