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Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21.
Zhang, Cuiyan; Li, Xiaotong; Adelmant, Guillaume; Dobbins, Jessica; Geisen, Christoph; Oser, Matthew G; Wucherpfenning, Kai W; Marto, Jarrod A; Kaelin, William G.
  • Zhang C; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215;
  • Li X; State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102, China;
  • Adelmant G; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215; Blais Proteomics Center, Dana-Farber Cancer Institute, Boston, MA 02215; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02215;
  • Dobbins J; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02215;
  • Geisen C; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215; Howard Hughes Medical Institute, Chevy Chase, MD 20815.
  • Oser MG; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215;
  • Wucherpfenning KW; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02215;
  • Marto JA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215; Blais Proteomics Center, Dana-Farber Cancer Institute, Boston, MA 02215; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02215;
  • Kaelin WG; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215; Howard Hughes Medical Institute, Chevy Chase, MD 20815 william_kaelin@dfci.harvard.edu.
Proc Natl Acad Sci U S A ; 112(50): 15372-7, 2015 Dec 15.
Article en En | MEDLINE | ID: mdl-26631746
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Péptidos / Proteínas Represoras / Proteínas Nucleares / Proteínas Ligasas SKP Cullina F-box / Proteínas F-Box / Proteolisis Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Péptidos / Proteínas Represoras / Proteínas Nucleares / Proteínas Ligasas SKP Cullina F-box / Proteínas F-Box / Proteolisis Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article