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Antimalarial and insecticidal activities of newly synthesized derivatives of Benzimidazole.
Kamil, Arfa; Akhter, Shamim; Ahmed, Maryam; Rizwani, Ghazala H; Hassan, Sohail; Naeem, Sabahat; Jahan, Sarwat; Khursheed, Raheela; Zahid, Hina.
  • Kamil A; Department of Pharmaceutical Chemistry, Federal Urdu University of Arts, Science and Technology, Karachi, Pakistan.
  • Akhter S; Department of Pharmaceutical Chemistry, University of Karachi, Karachi, Pakistan.
  • Ahmed M; Department of Pharmacognosy, Federal Urdu University of Arts, Science and Technology, Karachi, Pakistan.
  • Rizwani GH; Department of Pharmacognosy, University of Karachi, Karachi, Pakistan.
  • Hassan S; Department of Pharmaceutical Chemistry, University of Karachi, Karachi, Pakistan.
  • Naeem S; Dow College of Pharmacy, Dow University of Health Sciences, Karachi, Pakistan.
  • Jahan S; Department of Pharmaceutical Chemistry, Federal Urdu University of Arts, Science and Technology, Karachi, Pakistan.
  • Khursheed R; Department of Pharmacognosy, University of Karachi, Karachi, Pakistan.
  • Zahid H; Department of Pharmacognosy, University of Karachi, Karachi, Pakistan.
Pak J Pharm Sci ; 28(6): 2179-84, 2015 Nov.
Article en En | MEDLINE | ID: mdl-26639510
The bioactive benzimidazole and corresponding substituted phenacyl halides has been synthesized (11) new derivatives out of three compounds 8, 10 and 11 were found to inhibit the Plasmodium falciparum moderately after 72 hours of incubation hence acting as antimalarial agents. While these derivatives were exhibited negligible insecticidal activity too when analyzed by impregnated filter paper method.
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Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / Bencimidazoles / Insecticidas / Antimaláricos Idioma: En Año: 2015 Tipo del documento: Article
Search on Google
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PubMed Links

Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / Bencimidazoles / Insecticidas / Antimaláricos Idioma: En Año: 2015 Tipo del documento: Article