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Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations.
Lorenz, Susanne; Barøy, Tale; Sun, Jinchang; Nome, Torfinn; Vodák, Daniel; Bryne, Jan-Christian; Håkelien, Anne-Mari; Fernandez-Cuesta, Lynnette; Möhlendick, Birte; Rieder, Harald; Szuhai, Karoly; Zaikova, Olga; Ahlquist, Terje C; Thomassen, Gard O S; Skotheim, Rolf I; Lothe, Ragnhild A; Tarpey, Patrick S; Campbell, Peter; Flanagan, Adrienne; Myklebost, Ola; Meza-Zepeda, Leonardo A.
  • Lorenz S; Department of Tumor Biology, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway.
  • Barøy T; Norwegian Cancer Genomics Consortium, Norway.
  • Sun J; Department of Tumor Biology, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway.
  • Nome T; Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
  • Vodák D; Genomics Core Facility, Department of Core Facilities, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway.
  • Bryne JC; Norwegian Cancer Genomics Consortium, Norway.
  • Håkelien AM; Department of Molecular Oncology, Institute for Cancer research, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway.
  • Fernandez-Cuesta L; Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
  • Möhlendick B; Department of Tumor Biology, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway.
  • Rieder H; Department of Tumor Biology, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway.
  • Szuhai K; Genomics Core Facility, Department of Core Facilities, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway.
  • Zaikova O; Department of Tumor Biology, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway.
  • Ahlquist TC; Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, University of Cologne, Cologne, Germany.
  • Thomassen GO; Genetic Cancer Susceptibility Group, International Agency for Research on Cancer (IARC-WHO), Lyon, France.
  • Skotheim RI; Institute for Human Genetics, University Hospital Düsseldorf, Düsseldorf, Germany.
  • Lothe RA; Institute for Human Genetics, University Hospital Düsseldorf, Düsseldorf, Germany.
  • Tarpey PS; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands.
  • Campbell P; Clinic for Cancer, Surgery and Transplantation, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway.
  • Flanagan A; Department of Molecular Oncology, Institute for Cancer research, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway.
  • Myklebost O; Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
  • Meza-Zepeda LA; Department of Molecular Oncology, Institute for Cancer research, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway.
Oncotarget ; 7(5): 5273-88, 2016 Feb 02.
Article en En | MEDLINE | ID: mdl-26672768
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Osteosarcoma / Genes p53 / Reparación del ADN Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Osteosarcoma / Genes p53 / Reparación del ADN Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article