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Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis.
Mole, Damian J; Webster, Scott P; Uings, Iain; Zheng, Xiaozhong; Binnie, Margaret; Wilson, Kris; Hutchinson, Jonathan P; Mirguet, Olivier; Walker, Ann; Beaufils, Benjamin; Ancellin, Nicolas; Trottet, Lionel; Bénéton, Véronique; Mowat, Christopher G; Wilkinson, Martin; Rowland, Paul; Haslam, Carl; McBride, Andrew; Homer, Natalie Z M; Baily, James E; Sharp, Matthew G F; Garden, O James; Hughes, Jeremy; Howie, Sarah E M; Holmes, Duncan S; Liddle, John; Iredale, John P.
  • Mole DJ; Medical Research Council Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK.
  • Webster SP; Clinical Surgery, University of Edinburgh, Edinburgh, UK.
  • Uings I; University/British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
  • Zheng X; Discovery Partnerships with Academia, GlaxoSmithKline, Stevenage, UK.
  • Binnie M; Medical Research Council Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK.
  • Wilson K; University/British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
  • Hutchinson JP; University/British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
  • Mirguet O; Molecular Discovery Research, GlaxoSmithKline, Stevenage, UK.
  • Walker A; Flexible Discovery Unit, GlaxoSmithKline, Paris, France.
  • Beaufils B; Discovery Partnerships with Academia, GlaxoSmithKline, Stevenage, UK.
  • Ancellin N; Flexible Discovery Unit, GlaxoSmithKline, Paris, France.
  • Trottet L; Flexible Discovery Unit, GlaxoSmithKline, Paris, France.
  • Bénéton V; Flexible Discovery Unit, GlaxoSmithKline, Paris, France.
  • Mowat CG; Flexible Discovery Unit, GlaxoSmithKline, Paris, France.
  • Wilkinson M; EastChem School of Chemistry, University of Edinburgh, Edinburgh, UK.
  • Rowland P; EastChem School of Chemistry, University of Edinburgh, Edinburgh, UK.
  • Haslam C; Molecular Discovery Research, GlaxoSmithKline, Stevenage, UK.
  • McBride A; Molecular Discovery Research, GlaxoSmithKline, Stevenage, UK.
  • Homer NZ; University/British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
  • Baily JE; Mass Spectrometry Core, University of Edinburgh, Edinburgh, UK.
  • Sharp MG; University/British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
  • Garden OJ; Central Bioresearch Services, University of Edinburgh, Edinburgh, UK.
  • Hughes J; Clinical Surgery, University of Edinburgh, Edinburgh, UK.
  • Howie SE; Medical Research Council Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK.
  • Holmes DS; Medical Research Council Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK.
  • Liddle J; Discovery Partnerships with Academia, GlaxoSmithKline, Stevenage, UK.
  • Iredale JP; Discovery Partnerships with Academia, GlaxoSmithKline, Stevenage, UK.
Nat Med ; 22(2): 202-9, 2016 Feb.
Article en En | MEDLINE | ID: mdl-26752518
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pancreatitis / Propionatos / Benzoxazoles / ARN Mensajero / Oxazolidinonas / Quinurenina 3-Monooxigenasa / Insuficiencia Multiorgánica Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pancreatitis / Propionatos / Benzoxazoles / ARN Mensajero / Oxazolidinonas / Quinurenina 3-Monooxigenasa / Insuficiencia Multiorgánica Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article