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Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity.
Zhang, Li; Jiang, Cheng-Shi; Gao, Li-Xin; Gong, Jing-Xu; Wang, Zhong-Hua; Li, Jing-Ya; Li, Jia; Li, Xu-Wen; Guo, Yue-Wei.
  • Zhang L; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.
  • Jiang CS; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China; School of Biological Science and Technology, University of Jinan, 336, Nan Xin Zhuang Xi Road, Jinan, Shandong 250022, P
  • Gao LX; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.
  • Gong JX; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.
  • Wang ZH; School of Chemical and Environmental Engineering, Shanghai Institute of Technology, 100 Hai Quan Road, Fengxian Dictrict, Shanghai 201418, PR China.
  • Li JY; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.
  • Li J; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.
  • Li XW; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China. Electronic address: xwli@simm.ac.cn.
  • Guo YW; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China. Electronic address: ywguo@simm.ac.cn.
Bioorg Med Chem Lett ; 26(3): 778-781, 2016 Feb 01.
Article en En | MEDLINE | ID: mdl-26774579
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oxadiazoles / Diseño de Fármacos / Alcaloides Indólicos / Inhibidores Enzimáticos / Proteína Tirosina Fosfatasa no Receptora Tipo 1 Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oxadiazoles / Diseño de Fármacos / Alcaloides Indólicos / Inhibidores Enzimáticos / Proteína Tirosina Fosfatasa no Receptora Tipo 1 Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article