Photoresponsive Formation of an Intermolecular Minimal G-Quadruplex Motif.
Angew Chem Int Ed Engl
; 55(8): 2738-42, 2016 Feb 18.
Article
en En
| MEDLINE
| ID: mdl-26805928
ABSTRACT
The ability of three different bifunctional azobenzene linkers to enable the photoreversible formation of a defined intermolecular two-tetrad G-quadruplex upon UV/Vis irradiation was investigated. Circular dichroism and NMR spectroscopic data showed the formation of G-quadruplexes with K(+) â
ions at room temperature in all three cases with the corresponding azobenzene linker in an Eâ
conformation. However, only the para-para-substituted azobenzene derivative enables photoswitching between a nonpolymorphic, stacked, tetramolecular G-quadruplex and an unstructured state after E-Zâ
isomerization.
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Banco de datos:
MEDLINE
Asunto principal:
G-Cuádruplex
Idioma:
En
Año:
2016
Tipo del documento:
Article