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Chemical modifications in the seed region of miRNAs 221/222 increase the silencing performances in gastrointestinal stromal tumor cells.
Durso, Montano; Gaglione, Maria; Piras, Linda; Mercurio, Maria Emilia; Terreri, Sara; Olivieri, Michele; Marinelli, Luciana; Novellino, Ettore; Incoronato, Mariarosaria; Grieco, Paolo; Orsini, Gaetano; Tonon, Giancarlo; Messere, Anna; Cimmino, Amelia.
  • Durso M; Institute of Genetic and Biophysics "Adriano Buzzati Traverso", CNR, Via Pietro Castellino 111, 80131 Naples, Italy.
  • Gaglione M; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Via Vivaldi 43, 81100 Caserta, Italy.
  • Piras L; National Research Council-CNR, Institute of Crystallography-IC, Via G. Amendola, 122/O, 70126 Bari, Italy.
  • Mercurio ME; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Via Vivaldi 43, 81100 Caserta, Italy.
  • Terreri S; Institute of Genetic and Biophysics "Adriano Buzzati Traverso", CNR, Via Pietro Castellino 111, 80131 Naples, Italy.
  • Olivieri M; Institute of Genetic and Biophysics "Adriano Buzzati Traverso", CNR, Via Pietro Castellino 111, 80131 Naples, Italy.
  • Marinelli L; Department of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, 80131 Napoli, Italy.
  • Novellino E; Department of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, 80131 Napoli, Italy.
  • Incoronato M; Fondazione IRCCS SDN, Naples, Italy.
  • Grieco P; Department of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, 80131 Napoli, Italy.
  • Orsini G; Bioker srl, Multimedica spa, Naples, Italy.
  • Tonon G; Bioker srl, Multimedica spa, Naples, Italy.
  • Messere A; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Via Vivaldi 43, 81100 Caserta, Italy. Electronic address: anna.messere@unina2.it.
  • Cimmino A; Institute of Genetic and Biophysics "Adriano Buzzati Traverso", CNR, Via Pietro Castellino 111, 80131 Naples, Italy. Electronic address: cimmino@igb.cnr.it.
Eur J Med Chem ; 111: 15-25, 2016 Mar 23.
Article en En | MEDLINE | ID: mdl-26854374
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosfatos / Silenciador del Gen / MicroARNs / Tumores del Estroma Gastrointestinal Límite: Animals Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosfatos / Silenciador del Gen / MicroARNs / Tumores del Estroma Gastrointestinal Límite: Animals Idioma: En Año: 2016 Tipo del documento: Article