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Extending (Q)SARs to incorporate proprietary knowledge for regulatory purposes: A case study using aromatic amine mutagenicity.
Ahlberg, Ernst; Amberg, Alexander; Beilke, Lisa D; Bower, David; Cross, Kevin P; Custer, Laura; Ford, Kevin A; Van Gompel, Jacky; Harvey, James; Honma, Masamitsu; Jolly, Robert; Joossens, Elisabeth; Kemper, Raymond A; Kenyon, Michelle; Kruhlak, Naomi; Kuhnke, Lara; Leavitt, Penny; Naven, Russell; Neilan, Claire; Quigley, Donald P; Shuey, Dana; Spirkl, Hans-Peter; Stavitskaya, Lidiya; Teasdale, Andrew; White, Angela; Wichard, Joerg; Zwickl, Craig; Myatt, Glenn J.
  • Ahlberg E; AstraZeneca, Mölndal, Sweden.
  • Amberg A; Sanofi-Aventis Deutschland GmbH, Frankfurt, Germany.
  • Beilke LD; Toxicology Solutions, San Diego, CA, USA.
  • Bower D; Leadscope, Columbus, OH, USA.
  • Cross KP; Leadscope, Columbus, OH, USA.
  • Custer L; Bristol-Myers Squibb Co., New Brunswick, NJ, USA.
  • Ford KA; Genentech, South San Francisco, USA.
  • Van Gompel J; Janssen Research and Development, Beerse, Belgium.
  • Harvey J; GlaxoSmithKline, Ware, UK.
  • Honma M; National Institute of Health Sciences, Tokyo, Japan.
  • Jolly R; Eli Lilly and Company, Indianapolis, IN, USA.
  • Joossens E; European Commission Joint Research Centre, Ispra, Italy.
  • Kemper RA; Vertex, Boston, MA, USA.
  • Kenyon M; Pfizer, Groton, CT, USA.
  • Kruhlak N; FDA Center for Drug Evaluation and Research, Silver Spring, MD, USA.
  • Kuhnke L; Bayer HealthCare, Berlin, Germany.
  • Leavitt P; Bristol-Myers Squibb Co., New Brunswick, NJ, USA.
  • Naven R; Pfizer, Groton, CT, USA.
  • Neilan C; Incyte Corporation, Wilmington, DE, USA.
  • Quigley DP; Leadscope, Columbus, OH, USA.
  • Shuey D; Incyte Corporation, Wilmington, DE, USA.
  • Spirkl HP; Sanofi-Aventis Deutschland GmbH, Frankfurt, Germany.
  • Stavitskaya L; FDA Center for Drug Evaluation and Research, Silver Spring, MD, USA.
  • Teasdale A; AstraZeneca, Cheshire, England, UK.
  • White A; GlaxoSmithKline, Ware, UK.
  • Wichard J; Bayer HealthCare, Berlin, Germany.
  • Zwickl C; Eli Lilly and Company, Indianapolis, IN, USA.
  • Myatt GJ; Leadscope, Columbus, OH, USA. Electronic address: gmyatt@leadscope.com.
Regul Toxicol Pharmacol ; 77: 1-12, 2016 Jun.
Article en En | MEDLINE | ID: mdl-26879463
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mutagénesis / Bases del Conocimiento / Minería de Datos / Aminas / Pruebas de Mutagenicidad / Mutágenos Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mutagénesis / Bases del Conocimiento / Minería de Datos / Aminas / Pruebas de Mutagenicidad / Mutágenos Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article